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About Tasly

Silybin Capsules (Shuilin Jia)

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Indications: Used for the recovery of liver function abnormalities in acute and chronic hepatitis and fatty liver

Approval date: March 26, 2007

Date of revision: August 27, 2009 November 24, 2009 June 25, 2012 October 17, 2013 April 08, 2014

Please read the instructions carefully and use under the guidance of a physician

【Drug Name】

Common name: Silybin capsules

Name of commodity: 水 林佳

English name: Silibinin Capsules

Chinese Pinyin: Shuifeijibin Jiaonang

[Ingredients]

Silybin. Chemical name: 2α- [2,3-trans-2,3-dihydro-3- (4-hydroxy-3-methoxyphenyl) -2-hydroxymethyl-1,4-benzodioxy Hexacyclic-6-yl] -2,3-dihydro-3β, 5,7-trihydroxy-4H-1-benzopyran-4-one-hydrate. 2α- [2,3-trans-2,3-dihydro-3- (4-hydroxy-3-methoxyphenyl) -2- (hydroxymethyl) -1,4-benzodioxan-6-yl] -2,3-dihydro- 3β, 5,7-trihydroxy-4H-1-Benzopyran-4-one monohydrate

Molecular formula: C 25 H 22 O 10. H 2 O

Molecular weight: 500.47

[Character] Hard capsule, the content is white-like or light yellow powder.

[Specifications] 35mg silibinin per capsule

[Usage and Dosage] Oral, 2 to 4 capsules three times daily for adults; or as directed by a doctor.

[Adverse reactions] Mainly manifested as mild gastrointestinal symptoms (nausea, hiccups) and chest tightness.

[Taboo] is not clear.

[Caution] Use with caution to allergic to this product.

[Medication for pregnant and lactating women] The safety of medication for pregnant and lactating women has not been determined. Please follow the doctor's advice.

[Children's medication] No adverse reactions have been reported. Please follow your doctor's advice.

[Medicine for the elderly] No adverse reactions have been reported, please follow your doctor's advice.

[Drug interaction] is not clear.

[Drug overdose] No adverse reactions have been reported. Please follow your doctor's advice.

[Pharmacology and Toxicology]

Pharmacological effects: Silybin can stabilize the liver cell membrane, protect the enzyme system of liver cells, and eliminate reactive oxygen free radicals in liver cells, thereby improving the detoxification ability of the liver, avoiding long-term exposure of liver cells to poisons, taking liver toxicity drugs, smoking , Drinking, etc. were damaged.

【Pharmacokinetics】

According to literature reports, after taking silibinin lecithin complex 360mg (as silibinin) in healthy people, the peak free blood concentration was 298 ± 96ng / ml, and the peak time was 1.6 ± 0.3h. The residual time was 3.6 ± 0.4h, and the AUC (0-12h) was: 881 ± 207ng / ml · h.

[Storage] Sealed and stored in a dry place at room temperature.

[Packing] Aluminum foil-PVC / PVDC solid pharmaceutical compound hard blister packaging for pharmaceutical packaging, 10 tablets / board, 2 plates / box

Aluminum foil-PVC / PVDC solid pharmaceutical compound rigid blister packaging for pharmaceutical packaging, 10 tablets / board, 3 plates / box

Aluminum foil-PVC / PVDC solid pharmaceutical compound rigid blister pack for pharmaceutical packaging, 10 capsules / board, 6 boards / box

[Validity] 24 months

[Executive standards] State Food and Drug Administration National Drug Standard WS1- (X-234) -2004Z

[Chinese Medicine Approval Number]: Chinese Medicine Standard H20040299

【manufacturer】